Research Progress
- Oxidation-responsive OEGylated poly-L-cysteine and solution properties studies
- Effects of the surface charge on the stability of PEG-b-PCL micelles: simulation of the interactions between charged micelles and plasma components
- Supramolecular Hydrogels Assembled from Nonionic Poly(ethylene glycol)-b-Polypeptide Diblock Containing OEGylated Poly-L-glutamate
- Surface-Induced Hydrogelation Inhibits Platelet Aggregation
- Stimuli-responsive polypeptide materials prepared by ring-opening polymerization of α-amino acid N-carboxyanhydrides
- Effects of molecular weight on thermal responsive property of PEGylated poly-L-glutamates
- Facile Synthesis of Dendrimers Combining aza-Michael Addition with Thiol-yne Click Chemistry
- Peptide Hydrogels Assembled from Nonionic Alkyl-polypeptide Amphiphiles Prepared by Ring-Opening Polymerization
- SYNTHESIS OF TOOTHBRUSH COPOLYPEPTIDES BASED ON POLYLYSINE BACKBONE
- One-step synthesis of water dispersible silica nanoplates
- Conformation-specific Self-assembly of Thermo-responsive Poly(ethylene glycol)-b-polypeptide Diblock Copolymer
- Coassembly of Poly(ethylene glycol)-block-Poly(glutamate sodium) and Gemini Surfactants with Different Spacer Lengths
- Thermoresponsive Oligo(ethylene glycol) Functionalized Poly‑L‑cysteine
Peptide Hydrogels Assembled from Nonionic Alkyl-polypeptide Amphiphiles Prepared by ROP
Peptide Hydrogels Assembled from Nonionic Alkyl-polypeptide Amphiphiles Prepared by Ring-Opening Polymerization
Chongyi Chen , Decheng Wu , Wenxin Fu*, and Zhibo Li*
Biomacromolecules, 2013, 14 (8), 2494–2498
Three alkyl-polypeptide (AP) amphiphiles were prepared using ring-opening polymerization of α-amino acid N-carboxyanhydride. The polypeptide segment was composed of diethylene-glycol-monomethyl-ether-functionalized poly-L-glutamate (poly-L-EG2Glu). These AP amphiphiles can spontaneously self-assemble into transparent hydrogels in water. These hydrogels showed shear thinning properties, and their strength can be modulated by hydrophobic alkyl tails. CryoTEM and AFM characterizations suggested that these hydrogels were formed by nanoribbons arising from intermolecular interactions between nonionic poly-L-EG2Glu segments.
