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Injectable hydrogel based on polypeptides

  Biodegradable injectable hydrogels have shown important application prospect as biomedical polymer materials. Based on natural amino acids, thermo-responsive polypeptide materials have been prepared to construct injectable and thermo-responsive hydrogels via molecular design and controllable ring-opening polymerization. The synthesis technique of controllable ring-opening polymerization was adopted to avoid the tedious procedures with high cost during the solid-phase peptide synthesis while keeping physical and biofunctional properties.

Chen, C. ; Wu, D-C. ; Fu, W-X. ; Li, Z. Biomacromolecules, 2013, ASAP.