1. B. Liu, J. G. Liu, F. X. Liang, Q. Wang, C. L. Zhang, X. Z. Qu, J. L. Li, D. Qiu, Z. Z. Yang*, “Robust anisotropic composite particles with tunable Janus balance”, Macromolecules 2012, 45, 5176-5184.
We report a general emulsion approach to protrude a lobe by swelling the polymer core from a core−shell structure, achieving anisotropic Janus composite particles with tunable chemistry, shape, size, and size ratio of the two parts thus Janus balance.
2. L. J. Zhu, L. L. Zhao, X. Z. Qu*, Z. Z. Yang*, “pH-sensitive polymeric vesicles from coassembly of amphiphilic cholate grafted poly(L-lysine) and acid-cleavable polymer-drug conjugate”, Langmuir 2012, 28, 11988-11996.
Herein we report a coassembly method toward the preparation of pH-sensitive polymeric vesicular aggregates, using comb-shaped amphiphilic polymers, i.e., cholate grafted poly(L-lysine) (PLL-CA), with an amphiphilic poly(ethylene glycol)−doxorubicin conjugate (PEG-DOX).
3. H. Q. Jin, H. Tan, L. L. Zhao, W. P. Sun, L. J. Zhu, Y. G. Sun, H. J. Hao, H. Y. Xing, L. L. Liu, X. Z. Qu*, Y. N. Huang*, Z. Z. Yang*, “Ultrasound-triggered thrombolysis using urokinase-loaded nanogels”, Int. J. Pharm. 2012, 434, 384-390.
Urokinase-type plasminogen activator (uPA) was encapsulated into hollow nanogels which are generated by the reaction of glycol chitosan and aldehyde capped poly(ethylene glycol) (OHC-PEG-CHO) through a one-step approach of ultrasonic spray.
4. J. Li, Y. H. Wang, C. L. Zhang*, F. X. Liang, X. Z. Qu, J. L. Li, Q. Wang, D. Qiu, Z. Z. Yang*, “Janus polymeric cages”, Polymer 2012, 53, 3712-3718.
Janus polymeric cages are fabricated by Pickering emulsion interfacial polymerization.
5. D. L. Hu, X. Zhang, C. L. Zhang, S. J. Ding*, Z. Z. Yang*, “Quaternized polystyrene composite hollow particles”, Polymer 2012, 53, 3802-3806.
The crosslinked gel hollow templates are robust sufficiently to preserve their spherical contour during template synthesis. The gel shell with positively charged functional groups is infiltrative, and then a diversity of species can be loaded into the gel by electrostatic interaction.
6. X. L. Yu, F. X. Liang, J. G. Liu*, Y. F. Lu, Z. Z. Yang*, “Mesoporous hollow spheres from soap bubbling”, J. Colloid Interf. Sci. 2012, 367, 531-536.
In the presence of a bubble blowing agent, hollow spheres can be prepared by bubbling a silica sol. Herein, the trapped gas inside the bubble acts as a template.Whenthe porogen, i.e., other surfactant, is introduced, a mesostructured shell forms by the co-assembly with the silica sol during sol–gel process.
7. H. Tan, H. Q. Jin, H. C. Mei, L. J. Zhu, W. Wei, Q. Wang, F. X. Liang, C. L. Zhang, J. L. Li, X. Z. Qu*, D. H. Shangguan, Y. N. Huang, Z. Z. Yang*, “PEG-urokinase nanogels with enhanced stability and controllable bioactivity”, Soft Matter 2012, 8, 2644-2650.
Protein nanogels were synthesized via a one-step reaction procedure by crosslinking urokinase with benzaldehyde bifunctionalized poly(ethylene glycol).
8. J. F. Guo, W. P. Cheng, J. X. Gu, C. X. Ding, X. Z. Qu, Z. Z. Yang, C. O’Driscoll*, “Systemic delivery of therapeutic small interfering RNA using a pH-triggered amphiphilic poly-l-lysine nanocarrier to suppress prostate cancer growth in mice”, Eur. J. Pharm. Sci. 2012, 45, 521-532.
Amphiphilic polycations with “stealth” capacity have previously been synthesised by PEGylation of poly-L-lysine-cholic acid (PLL-CA).
9. Y. Chen, F. X. Liang*, H. L. Yang, C. L. Zhang, Q. Wang, X. Z. Qu, J. L. Li, Y. L. Cai*, D. Qiu, Z. Z. Yang*, “Janus nanosheets of polymer-inorganic layered composites”, Macromolecules 2012, 45, 1460-1467.
Janus nanosheets of polymer−inorganic layered composites are fabricated by crushing the corresponding Janus composite hollow spheres, which are synthesized by materialization of an amphiphilic emulsion interface with self-organized sol−gel process and subsequent polymer grafting onto the lipophilic side.
10. D. Wang, P. W. Jiao, J. M. Wang, Q. L. Zhang, L. Feng*, Z. Z. Yang*, “Fast photo-switched wettability and color of surfaces coated with polymer brushes containing spiropyran”, J. Appl. Polym. Sci. 2012,125,870-875.
An intelligent photo-responsive spiropyran (SP)-contained surface that combines reversible wettability conversion with photochromic behavior was prepared on etched silicon substrates by atom transfer radical polymerization.